Within our study, we ended up capable of significantly escalate the dose of CX-5461 outside of that attained in the first-in-human analyze in sufferers with hematologic cancers. The RP2D of 475?mg/m2 on times one, eight, and 15 of the four-7 days cycle, was depending on phototoxicity, which happened Regardless of stringent UV light-weight avoidance